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Abstract #5524

Multi-region Semi-Adiabatic Spectral-Spatial Spectroscopic Imaging (SASSI) sequence for accelerated MRSI at 7T

Rebecca Emily Feldman1 and Priti Balchandani1

1Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States

High field MRI permits us to leverage increased signal-to-noise ratio (SNR) and spectral separation between metabolite peaks for more sensitive metabolite detection at higher spatial resolutions. However, the acquisition of high-resolution spectral grids can be prohibitively time intensive. Accelerated MRSI acquisitions are challenged by the limitations at 7T. We develop a multi-region SPSP excitation pulse and use it to create a novel low power, B1 insensitive multi-region SASSI sequence with minimal chemical shift to enable accelerated MRSI.

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