Abstract #5566

Comparison of Gd-DTPA-BMA versus Gd-DOTA of Gadolinium retention in human bone tissue with renal function

Takaki Maeda¹, Hitomi Hara², Toshihiro Akisue², Yuki Iwama³, Ryosuke Kuroda², Masahiko Fujii⁴, and Kazuro Sugimura⁵

¹Radiology, Kobe University Hospital, Kobe, Japan, ²Orthopedic Surgery, Kobe University Graduate School of Medicine, ³Radiology, Hyogo Prefectural Nishinomiya Hospital, ⁴Kobe Minimally Invasive Cancer Center, ⁵Kobe University Graduate School of Medicine

The purpose of this study was to determine the gadolinium (Gd) retention in human bone tissue after administration of Gd contrast agent such as macrocyclic (Gd-DOTA) or linear (Gd-DTPA-BMA) chelate at a standard single clinical dose and to evaluate its correlation with renal function.

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