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Abstract #5566

Comparison of Gd-DTPA-BMA versus Gd-DOTA of Gadolinium retention in human bone tissue with renal function

Takaki Maeda1, Hitomi Hara2, Toshihiro Akisue2, Yuki Iwama3, Ryosuke Kuroda2, Masahiko Fujii4, and Kazuro Sugimura5

1Radiology, Kobe University Hospital, Kobe, Japan, 2Orthopedic Surgery, Kobe University Graduate School of Medicine, 3Radiology, Hyogo Prefectural Nishinomiya Hospital, 4Kobe Minimally Invasive Cancer Center, 5Kobe University Graduate School of Medicine

The purpose of this study was to determine the gadolinium (Gd) retention in human bone tissue after administration of Gd contrast agent such as macrocyclic (Gd-DOTA) or linear (Gd-DTPA-BMA) chelate at a standard single clinical dose and to evaluate its correlation with renal function.

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