Parallel imaging and spectroscopy are facilitated by multi-channel phased array coils. An important step is the combination of individual data from each channel, yet the effect of the non-uniformity of array coils on signal-to-noise ratio (SNR) is poorly characterized. Here, we present a systematic framework for identifying vulnerabilities in phased array coils for MRS. We demonstrate the importance of voxel position and coil proximity on overall SNR in a phantom and human subject, with significant SNR improvements after selectively filtering individual spectra based on pre-determined SNR thresholds which must be optimized for each phased array coil and volume of interest.
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