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Abstract #0004

Caval Blood Flow Distribution in Fontan Circulation: Comparison between ASL-Measured Pulmonary Perfusion and 4D Flow

Joshua S. Greer1,2, Jerry Michael3, Barbara Burkhardt3, Animesh Tandon2,3, Gerald F. Greil2,3,4, Tarique Hussain2,3, and Ananth J. Madhuranthakam2,4

1Bioengineering, University of Texas at Dallas, Richardson, TX, United States, 2Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 3Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States, 4Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Caval flow contribution to each lung is of interest in Fontan circulation due to the increased risk of developing pulmonary arteriovenous malformations when flow is unevenly distributed. Existing methods to assess this risk are invasive and require ionizing radiation, posing additional risks to pediatric patients during longitudinal monitoring. In this study, we demonstrate a non-invasive, non-ionizing assessment of the origin of pulmonary blood flow, as well as quantitative pulmonary perfusion using arterial spin labeled MR, and compare with the previously proposed 4D-flow measurement of caval flow distribution.

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