Familial hypercholesterolemia (FH) is an autosomal dominant disorder of lipoprotein metabolism, that are associated with premature atherosclerosis, early-onset of cardiovascular disease (CVD) with an elevated mortality. It would be prudent to develop and investigate imaging-based hemodynamics biomarkers that assist in cardiovascular risk assessment of FH patients. In this work, we obtain several hemodynamics parameters in HP patients using a single methodology, which is based on the analysis of 4D flow data using a finite element method. We found distinctive biomarkers as WSS (magnitude, axial, circumferential) and Kinetic Energy those present more significant differences along the entire aorta.
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