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Abstract #0012

30 times accelerated 4D flow MRI in the carotids using a Pseudo Spiral Cartesian acquisition and a Total Variation constrained Compressed Sensing reconstruction

Eva S Peper1, Lukas M Gottwald1, Qinwei Zhang1, Bram F Coolen2, Pim van Ooij1, Gustav J Strijkers2, and Aart J Nederveen1

1Radiology and Nuclear Medicine, Academic Medical Center (AMC), Amsterdam, Netherlands, 2Biomedical Engineering and Physics, Academic Medical Center (AMC), Amsterdam, Netherlands

4D flow MRI enables visualization and quantification of complex blood flow, and provides relevant biomarkers, such as wall shear stress. A 4D flow MRI acquisition, however, takes between 15-40 min, which complicates its use in clinical practice. In this work, we developed a technique to reduce scan time by prospectively undersampling k-space in a pseudo-spiral Cartesian fashion. Combined with a Compressed Sensing reconstruction using a total variation sparsifying transform in time, this technique makes 4D flow MRI in the carotid arteries 20-30 times faster, while preserving accuracy in flow and wall shear stress measurements.

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