Abstract #0034

MP2RAGEME: T1, T2* and QSM mapping in one sequence at 7 Tesla

Matthan W.A. Caan^1,2, Pierre-Louis Bazin^2,3,4, Alessio Fracasso², José Marques⁵, Serge Dumoulin², and Wietske van der Zwaag²

¹Radiology, Academic Medical Center, Amsterdam, Netherlands, ²Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, ³Social Brain Laboratory, Netherlands Institute for Neuroscience, Amsterdam, Netherlands, ⁴Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, ⁵Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands

Quantitative T₁, T₂* and QSM information can be acquired in a single acquisition, using a multi-echo extension of the MP2RAGE sequence, MP2RAGEME. This simultaneous acquisition results in large time savings, perfectly coregistered data and minimal image quality differences. Following a correction for residual transmit B1-sensitivity quantitative T₁ and T₂* and QSM-values were in excellent agreement with those obtained from separately acquired MP2RAGE and GRE data. Values were also in correspondence with literature. From the MP2RAGEME data, a multiparametric cortical parcellation was obtained, as well as a combined arterial and venous map.

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