Quantitative T1, T2* and QSM information can be acquired in a single acquisition, using a multi-echo extension of the MP2RAGE sequence, MP2RAGEME. This simultaneous acquisition results in large time savings, perfectly coregistered data and minimal image quality differences. Following a correction for residual transmit B1-sensitivity quantitative T1 and T2* and QSM-values were in excellent agreement with those obtained from separately acquired MP2RAGE and GRE data. Values were also in correspondence with literature. From the MP2RAGEME data, a multiparametric cortical parcellation was obtained, as well as a combined arterial and venous map.