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Abstract #0034

MP2RAGEME: T1, T2* and QSM mapping in one sequence at 7 Tesla

Matthan W.A. Caan1,2, Pierre-Louis Bazin2,3,4, Alessio Fracasso2, José Marques5, Serge Dumoulin2, and Wietske van der Zwaag2

1Radiology, Academic Medical Center, Amsterdam, Netherlands, 2Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, 3Social Brain Laboratory, Netherlands Institute for Neuroscience, Amsterdam, Netherlands, 4Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 5Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands

Quantitative T1, T2* and QSM information can be acquired in a single acquisition, using a multi-echo extension of the MP2RAGE sequence, MP2RAGEME. This simultaneous acquisition results in large time savings, perfectly coregistered data and minimal image quality differences. Following a correction for residual transmit B1-sensitivity quantitative T1 and T2* and QSM-values were in excellent agreement with those obtained from separately acquired MP2RAGE and GRE data. Values were also in correspondence with literature. From the MP2RAGEME data, a multiparametric cortical parcellation was obtained, as well as a combined arterial and venous map.

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