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Abstract #0077

Volumetric Apparent Diffusion Coefficient Histogram Analysis in Differentiating Intrahepatic Cholangiocarcinoma from Hepatocellular Carcinoma

Xianlun Zou1, Yaqi Shen1, Zhen Li1, and Daoyu Hu1

1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Accurate differentiation between intrahepatic cholangiocarcinoma (IHCC) and hepatocellular carcinoma (HCC) is essential for adequate treatment planning. In the present study, non-contrast volumetric ADC histogram analysis was employed to differentiate IHCC (n=33) and HCC (n=98). The results suggested that except the kurtosis and skewness, all the volumetric ADC histogram parameters, were helpful in distinguishing IHCC from HCC. Among all the parameters, 75th percentile ADC was most helpful to distinguish the two diseases. This non-contrast method provides useful information in differentiating IHCC from HCC, it benefits patients who are contraindicate to contrast agents.

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