Abstract #0078

Motion Correction of Diffusion-weighted imaging in the analysis of Apparent Diffusion Coefficient for preoperative staging of hepatocellular carcinoma

Wu Zhou¹, Qiyao Wang², Guoxi Xie³, Fei Yan², Yaoqin Xie², Guangyi Wang⁴, Zaiyi Liu⁴, Changhong Liang⁴, Hairong Zheng², and Lijuan Zhang²

¹School of Medical Information Engineering, Guangzhou University of Chinese Medicine, Guangzhou, China, ²Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, ³Guangzhou Medical University, Guangzhou, China, ⁴Department of Radiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China

Preoperative tumor staging of hepatocellular carcinoma (HCC) is a critical issue that influences tumor recurrence and patient survival in clinical practice. One of the challenges encountered in DWI of the liver is cardiac motion that can affect the accuracy of ADC measurements, which may inevitably influence the performance of DWI for HCC staging. However, the impact of motion for ADC and HCC staging has not been thoroughly investigated. In this work, we quantitatively investigate the relationship of motion correction, ADC and staging of HCC in order to widen the understanding of applications in DWI for tumor assessment.

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