Abstract #0081

Using Tumor Stiffness as a Potential Biomarker for Predicting Hepatocellular Carcinoma Recurrence

Jin Wang¹, Hao Yang¹, Yong Liu², Sichi Kuang¹, Bingjun He¹, Yao Zhang¹, Qungang Shan¹, Jingbiao Chen¹, TianHui Zhang¹, Kevin J. Glaser³, Cairong Zhu⁴, Jun Chen³, Meng Yin³, Bogdan Dzyubak³, Sudhakar K. Venkatesh³, and Richard L. Ehman³

¹Department of Radiology, the Third Affiliated Hospital of Sun Yat-sen University(SYSU), Guangzhou, China, ²Department of Pathology, the Third Affiliated Hospital of Sun Yat-sen University(SYSU), Guangzhou, China, ³Department of Radiology, Mayo Clinic, Rochester, MN, United States, ⁴Department of Epidemiology and Biostatistics, West China School of Public Health Sichuan University, ChengDu, China

Hepatocellular carcinoma (HCC) is a highly aggressive cancer and one of the leading causes of cancer-related deaths around the world. Our preliminary analysis of 78HCCsshowed 3D MRE is a promising, noninvasive technique for predicting the early recurrence of HCCs after hepatic resection. MRE-assessed tumor stiffness correlates with features such as encapsulation, macrovascular invasion, and histological grade. In the future, larger studies will improve our understanding of the relationship between HCC stiffness, invasiveness, and outcome for better allocation of treatment strategies and surveillance follow-up.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.