Jin Wang1, Hao Yang1, Yong Liu2, Sichi Kuang1, Bingjun He1, Yao Zhang1, Qungang Shan1, Jingbiao Chen1, TianHui Zhang1, Kevin J. Glaser3, Cairong Zhu4, Jun Chen3, Meng Yin3, Bogdan Dzyubak3, Sudhakar K. Venkatesh3, and Richard L. Ehman3
1Department of Radiology, the Third Affiliated Hospital of Sun Yat-sen University(SYSU), Guangzhou, China, 2Department of Pathology, the Third Affiliated Hospital of Sun Yat-sen University(SYSU), Guangzhou, China, 3Department of Radiology, Mayo Clinic, Rochester, MN, United States, 4Department of Epidemiology and Biostatistics, West China School of Public Health Sichuan University, ChengDu, China
Hepatocellular carcinoma (HCC) is a highly aggressive cancer and one of the leading causes of cancer-related deaths around the world. Our preliminary analysis of 78HCCsshowed 3D MRE is a promising, noninvasive technique for predicting the early recurrence of HCCs after hepatic resection. MRE-assessed tumor stiffness correlates with features such as encapsulation, macrovascular invasion, and histological grade. In the future, larger studies will improve our understanding of the relationship between HCC stiffness, invasiveness, and outcome for better allocation of treatment strategies and surveillance follow-up.