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Abstract #0116

Translational Radiogenomics of Brain Tumors: From Lab-Invesigation to Clinical Application

Dieter Henrik Heiland1, Horst Urbach2, and Irina Mader3

1Department of Neurosurgery, Medical Center Freiburg, Freiburg, Germany, 2Department of Nueroradiology, Medical Center Freibrurg, Freibrurg, Germany, 3Medical Center Freiburg, Freiburg, Germany

The interpretation of radiogenomic findings and its biological or clinical meaning is currently discussed and still unknown. Therefrom, a translational approach is aimed for integration of laboratory investigations and radiogenomic findings resulting in meaningful integration of radiogenomic discoveries. The presented study aimed to explore the molecular background of a MR-Spectroscopy imaging. In a stepwise approach findings were validated on tissue samples and finally taken into glioma cell models.

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