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Abstract #0258

On the magnetic field and echo time dependence of the pseudo-diffusion coefficient

Andreas Julian Riexinger1, Andreas Wetscherek2, Jan Martin1, Tristan Anselm Kuder3, Armin Nagel1, Michael Uder1, Bernhard Hensel4, Lars Müller3,5, and Frederik Bernd Laun1

1Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 2Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom, 3Department Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 4Center for Medical Physics and Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 5CUBRIC, School of Psychology, Cardiff University, Cardiff, United Kingdom

It has been reported that a strong echo time dependence of the perfusion fraction f exists in liver and pancreas. The purpose of this work is to investigate whether a similar dependence exists for the pseudo-diffusion coefficient D*. Thereto, the livers of six healthy volunteers were examined at two echo times (TE = 40/80 ms) at two field strengths. In contrast to f, D* shows almost no echo time dependence in the healthy liver and the observed field strength dependence was smaller than the fit uncertainty.

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