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Abstract #0262

Simultaneous B1 and T1 Mapping Using Spiral Variable-Flip-Angle Acquisitions for Whole-Brain Coverage in Less Than One Minute

Rahel Heule1,2,3, Josef Pfeuffer4, Craig H. Meyer5, and Oliver Bieri1,2

1Division of Radiological Physics, Department of Radiology, University of Basel Hospital, Basel, Switzerland, 2Department of Biomedical Engineering, University of Basel, Basel, Switzerland, 3High Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 4Siemens Healthcare GmbH, Application Development, Erlangen, Germany, 5Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, United States

Rapid variable-flip-angle T1 mapping techniques are frequently applied in clinical settings, but their accuracy is often impaired by incomplete spoiling or flip angle miscalibrations. To eliminate these two error sources simultaneously, a combined B1 and T1 mapping method is proposed based on spiral 2D multislice spoiled gradient echo imaging with high spoiling efficiency. The transition to steady state is minimized by an optimized single preparation pulse. A single-shot spiral readout during the preparation module enables ultrafast B1 mapping and as a result reproducible bias-free T1 mapping with whole-brain coverage at clinically relevant resolution in less than one minute.

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