Abstract #0268

Comparison of 3D spoiled-gradient multiple echo with STEAM for proton density fat fraction and fatty acid composition estimation

Angéline Nemeth¹, Hélène Ratiney¹, Benjamin Leporq¹, Kévin Seyssel², Bérénice Segrestin³, Pierre-Jean Valette⁴, Martine Laville³, and Olivier Beuf¹

¹Univ. Lyon, INSA‐Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1206, F69621, VILLEURBANNE, France, Lyon, France, ²Department of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Lausanne, Switzerland, ³Centre de Recherche en Nutrition Humaine Rhône-Alpes (CRNH-RA), Centre Hospitalier Lyon Sud, Pierre-Bénite, Lyon, France, ⁴Hospices Civils de Lyon, Département d'imagerie digestive, CHU Edouard Herriot, Lyon, Lyon, France

A total of 39 volunteers underwent an imaging and spectroscopy protocol on a 3T Ingenia Philips system with an axial 3D spoiled-gradient multiple echo sequence on abdominal region and a set of three STEAM sequences acquired on subcutaneous adipose tissue, visceral adipose tissue and liver. The quantification of Proton density fat fraction (PDFF), proportion of saturated (SFA), monounsaturated (MUFA) or polyunsaturated (PUFA) fatty acids from both MRI and MRS methods were compared. Good correlation with a little bias was found for the liver PDFF. Values of PUFA, MUFA and SFA from both techniques were poorly correlated.

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