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Abstract #0268

Comparison of 3D spoiled-gradient multiple echo with STEAM for proton density fat fraction and fatty acid composition estimation

Angéline Nemeth1, Hélène Ratiney1, Benjamin Leporq1, Kévin Seyssel2, Bérénice Segrestin3, Pierre-Jean Valette4, Martine Laville3, and Olivier Beuf1

1Univ. Lyon, INSA‐Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1206, F69621, VILLEURBANNE, France, Lyon, France, 2Department of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Lausanne, Switzerland, 3Centre de Recherche en Nutrition Humaine Rhône-Alpes (CRNH-RA), Centre Hospitalier Lyon Sud, Pierre-Bénite, Lyon, France, 4Hospices Civils de Lyon, Département d'imagerie digestive, CHU Edouard Herriot, Lyon, Lyon, France

A total of 39 volunteers underwent an imaging and spectroscopy protocol on a 3T Ingenia Philips system with an axial 3D spoiled-gradient multiple echo sequence on abdominal region and a set of three STEAM sequences acquired on subcutaneous adipose tissue, visceral adipose tissue and liver. The quantification of Proton density fat fraction (PDFF), proportion of saturated (SFA), monounsaturated (MUFA) or polyunsaturated (PUFA) fatty acids from both MRI and MRS methods were compared. Good correlation with a little bias was found for the liver PDFF. Values of PUFA, MUFA and SFA from both techniques were poorly correlated.

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