Abstract #0270

Silent T1-Mapping Using the Variable Flip Angle Method with Zero Echo Time

Emil Ljungberg^1,2, Ana Beatriz Solana Sanchez², Tobias C Wood¹, Shannon Kolind^3,4,5, Florian Wiesinger², and Gareth J Barker¹

¹Neuroimaging, King's College London, London, United Kingdom, ²GE Healthcare, Munich, Germany, ³Medicine, University of British Columbia, Vancouver, BC, Canada, ⁴Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, ⁵Radiology, University of British Columbia, Vancouver, BC, Canada

In this work we present a silent whole brain T₁-mapping technique with zero echo time using a variable flip angle (VFA) scheme with a 3D radial sequence (RUFIS). The technique is compared to a conventional Cartesian gradient-echo based sequence (DESPOT1-HIFI) in a quantitative T₁ phantom as well as in vivo in a single subject. Phantom measurements showed good agreement between techniques with average difference of 28 ms. In vivo T₁ maps showed good correspondence between RUFIS and DESPOT1-HIFI.

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