Hyperpolarized silicon particles exhibit very long T1 relaxation at room temperature, making them favourable as novel imaging MR probes. It has recently been shown that silicon particles in the nanometer size range can be efficiently polarized and image even after 4 hours upon transfer of the sample to the imaging system.
The objective of the present work was to demonstrate the imaging capability of surface functionalized hyperpolarized nanometer size silicon particles in an experimental in-vivo setting.
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