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Abstract #0475

Effects of reconstruction with deformable motion correction on abdominal DCE-MRI images

Adam Johansson1, James M Balter1, and Yue Cao1,2,3

1Radiation Oncology, University of Michigan, Ann Arbor, MI, United States, 2Radiology, University of Michigan, Ann Arbor, MI, United States, 3Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States

Image reconstruction with deformable motion correction for dynamic contrast-enhanced (DCE) MRI can counteract artifacts in dynamic images and estimated perfusion maps. In this study, we present the results of applying a reconstruction method with deformable motion correction to 54 DCE-MRI examinations of 31 patients. Deformable motion correction is found to compensate for up to 15 mm of residual motion after rigid-body motion correction. Motion-correction also reduces liver-wide bias caused by motion-distorted input functions and removes localized artifacts at liver edges. Finally, for several cases, motion-correction makes lesion edges sharper in reconstructed images.

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