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Abstract #0476

3D non-rigid motion-corrected dynamic contrast enhanced MRI of the liver with high isotropic resolution

Matteo Ippoliti1, Marcus Makowski1,2, Tobias Schaeffter2,3, and Christoph Kolbitsch2,3

1Department of Radiology, Charité, Berlin, Germany, 2Division of Imaging Sciences and Biomedical Engineering, King’s College London, London, United Kingdom, 3Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany

Dynamic Contrast Enhanced (DCE) MRI of the liver is an important diagnostic tool. The main challenge is complex respiratory motion of the abdomen. Here we present a motion correction approach for DCE-MRI. Golden Radial Phase Encoding data was acquired continuously in a patient after contrast injection during free-breathing. In a first step, non-rigid respiratory motion was estimated from the data. The motion information was then used to reconstruct 3D motion corrected dynamic images with a temporal resolution of 13s and an isotropic spatial resolution of 1.5mm3. The proposed technique strongly reduced motion artefacts and ensured high image quality.

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