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Abstract #0478

Joint PET-MR image registration for cardiac and respiratory motion correction of simultaneous cardiac PET-MR

Christoph Kolbitsch1,2, Radhouene Neji2,3, Matthias Fenchel4, Andreas Schuh5, Andrew Mallia2, Paul Marsden2, and Tobias Schaeffter1,2

1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, 2Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom, 3MR Research Collaborations, Siemens Healthcare, Frimley, United Kingdom, 4MR R&D Collaborations, Siemens Medical Solutions, New York, NY, United States, 5Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, United Kingdom

Cardiac Positron Emission Tomography (PET) can provide diagnostic information about myocardial perfusion and metabolism with excellent sensitivity. The main challenge is physiological motion of the heart due to breathing and heartbeat. Here we present a joint PET-MR image registration approach which provides non-rigid cardiac and respiratory motion information utilising image data from a simultaneous PET-MR scan of less than 4min. In addition, attenuation correction information is also derived from the MR scan. The motion information is utilised in a motion-corrected PET image reconstruction which improves PET image quality, enhances visualisation of small features and increases measured uptake values by 22±7%.

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