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Abstract #0485

In Vivo Quantification of Aortic Stiffness in Abdominal Aortic Aneurysm Patients using MR Elastography: A Longitudinal Study

Huiming Dong1,2, Brian Raterman1, Xiaokui Mo3, Prateek Kalra1, Richard White1, and Arunark Kolipaka1

1Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States, 2Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States, 3Center for Biostatistics, The Ohio State University, Columbus, OH, United States

Abdominal aortic aneurysm (AAA) rupture causes death in 90% of AAA patients. Clinically, the rupture potential is evaluated using AAA diameter. Aortic stiffness can potentially provide more accurate rupture risk assessment. Therefore, the aim of this study is to use non-invasive MR elastography (MRE) to estimate aortic stiffness in AAA patients, and study the relationship between stiffness and AAA diameter. Results showed that aortic stiffness varied during the serial follow-up, demonstrating (1) no correlation between AAA stiffness and diameter, and (2) AAA diameter may not be an accurate indicator for rupture potential.

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