Abstract #0493

Flow Compensation in Dynamic Susceptibility Contrast MRI for an Increase in Arterial Input Function Precision

Benoît Bourassa-Moreau¹, Réjean Lebel¹, Guillaume Gilbert², David Mathieu³, and Martin Lepage¹

¹Centre d’imagerie moléculaire de Sherbrooke, Département de médecine nucléaire, Université de Sherbrooke, Sherbrooke, QC, Canada, ²MR Clinical Science, Philips Healthcare Canada, Markham, ON, Canada, ³Service de neurochirurgie, Département de chirurgie, Université de Sherbrooke, Sherbrooke, QC, Canada

Arterial input functions (AIF) measured inside major arteries in perfusion MRI are derived from the contrast agent induced changes in the blood signal. Such signal measurements of flowing blood are prone to (in)flow induced effects. Here, the effects of pulsatile blood flow are studied for AIF measurement in dynamic susceptibility contrast (DSC) with dual-echo single-shot EPI. First moment flow compensation is shown to partially recover the noise attributed to flow effects. The resulting signal-to-noise ratio is increased by a factor of 14 (2) in the middle (internal) carotid artery providing a more precise AIF for cerebral blood flow calculation.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.