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Abstract #0498

Evaluation of UTE for improved contrast enhanced DCE MRI at 7T

Naoharu Kobayashi1, Patrick Bolan1, and Gregory J. Metzger1

1Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, United States

We investigated the feasibility of using an ultrashort echo time (UTE) technique for DCE MRI imaging of prostate cancer patients at 7T to minimize the impact of the increased R2* relaxivity on signal enhancement curves and pharmacokinetic parameter assessment. The Gd concentration-time curves and pharmacokinetic parameter maps were compared to clinical DCE MRI at 3T. The proposed method achieved DCE MRI at 7T with a signal time course comparable to 3T DCE MRI but with increased SNR for improved spatial resolution and no R2* effects, which are exacerbated with increasing field.

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