Concussive blast traumatic brain injury (cbTBI) may benefit from evaluation with advanced MR imaging techniques. Here we report the results of a 5-year follow-up prospective, observational, longitudinal human cohort study evaluating cbTBI using arterial spin labeling, correlated with durable measures of long term outcome taken from an extensive battery of neurobehavioral, neuropsychological, and psychiatric evaluations. Specifically, service members who sustained combat-related cbTBI exhibited significant, regional hypoperfusion 5 years post-injury compared to combat-deployed controls, associated with measures of long term outcome.
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