Abstract #0586

Parallel transmission kT-points and CAIPIRIHNA accelerated MP2RAGE for ultra-high field anatomical imaging

Valentin G. Kemper^1,2, Federico De Martino^1,2,3, Elia Formisano^1,2, Tobias Kober^4,5,6, and Benedikt A. Poser^1,2

¹Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, ²MBIC - Maastricht Brain Imaging Center, Maastricht University, Maastricht, Netherlands, ³Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, ⁴Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ⁵Department of Radiology, University Hospital of Lausanne, Lausanne, Switzerland, ⁶LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

The MP2RAGE imaging sequence is widely used for T1 weighted anatomical imaging, especially at 7T, where B1 inhomogeneity may degrade the image quality. This study demonstrates an improved MP2RAGE sequence featuring kT-points parallel transmission excitation and CAIPIRINHA 2D acceleration for improved T1 weighted anatomical images of the living human brain at 7 T and 9.4 T. High resolution (0.6 mm and 0.45 mm isotropic) data with high contrast-to-noise ratio allow for improved cortical segmentation, e.g. for cortical laminar investigations. We further demonstrate a 6-fold accelerated whole brain CAIPIRINHA acquisition at 0.6 mm resolution in only 4:10 min.

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