Abstract #0588

Short-range functional connections at birth predict neurodevelopmental outcome at 2 years of age

Minhui Ouyang¹, Qinmu Peng^1,2, Michelle Slinger¹, and Hao Huang^1,2

¹Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, United States, ²Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

Short-range functional connectivity (FC) is the major contributor to overall significant FC increases around birth. With critical role of short-range FC in neonate brain maturation, we hypothesized that short-range FC at birth predicts the neurodevelopmental outcome at 2 years of age. We measured short-range FC with neonatal resting-state fMRI and used support vector regression (SVR) to predict cognitive scores at 2 years of age. A highly predictive model was achieved with inhomogeneous feature contribution pattern across cortical areas. Significant correlation was found between short-range FC strength in widespread brain regions at birth and cognitive scores at 2 years of age.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.