The goal of this study was to demonstrate the feasibility of prospective motion and shim correction for MRS at 7 Tesla. We combined an optical tracking system for motion correction and a shim navigator for first-order B0 shim correction into a semi-LASER sequence. The new sequence was validated in the prefrontal cortex, a region sensitive to motion due to susceptibility effects induced by the proximity of the nasal cavity. Results show excellent performance, with similar spectral quality (signal-to-noise ratio and linewidth) before, during, and after motion when both motion and shim navigators are used.
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