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Abstract #0627

Dynamic 23Na-Imaging of the Human Lung with Fully Flexible Intrinsic Respiratory Gating

Nicolas G.R. Behl1, Armin M. Nagel1,2, Reiner Umathum1, Florian Maier1, Mark E. Ladd1, Mark O. Wielp├╝tz3, Hans-Ulrich Kauczor3, and Tanja Platt1

1Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 2Institute of Radiology, University Hospital Erlangen, Erlangen, Germany, 3Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany

23Na lung MRI is a potential tool e.g. for investigating tumor viability and treatment response. The acquired data is, however, influenced by respiratory motion since breath-hold acquisitions are not possible due to the long measurement times. Here, we present a method for full flexibility in retrospective gating of 3D-radial data, combined with a Compressed-Sensing reconstruction. Up to 14 frames could be reconstructed from one in-vivo dataset, corresponding to a temporal resolution of 0.27 s. The temporal resolution of 23Na lung MRI could potentially lead to a more accurate quantification of the Tissue Sodium Concentration in the human torso.

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