T1 mapping of the cervical spinal cord at 7T with a 300-µm in-plane resolution using the MP2RAGE sequence is presented. A semi-automated post-processing pipeline enabled group studies (n=10 healthy subjects) with quantitative evaluation within small spinal cord sub-structures from C1 to C7, explored for the first time using T1 mapping. This work lays the groundwork for improved characterization of spinal cord degeneration using 7T MRI, by allowing investigation within particular relevant regions such as the anterior/posterior gray matter horns and ventromedial white matter tracts. It also offers new perspectives to build dedicated spinal cord substructures templates.
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