Abstract #0669

Spinal cord MRI and fMRI at 16.4 T during spinal cord stimulation in rats: initial experience

Hanne Laakso^1,2, Lauri J Lehto¹, Carlos Cuellar³, Igor Lavrov³, John Osborn⁴, Shalom Michaeli¹, and Silvia Mangia¹

¹Center for Magnetic Resonance in Research, University of Minnesota, Minneapolis, MN, United States, ²A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland, ³Neural Engineering Laboratory, Mayo Clinic, Rochester, MN, United States, ⁴Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, MN, United States

This study aims at paving the way for spinal cord MRI and fMRI during spinal cord stimulation (SCS) in rats, with the goal of providing an experimental framework for assessing the impact of SCS on neuroplasticity and functional circuitry. MRI and fMRI of the spinal cord during SCS are extremely challenging due to motion and electrode-induced susceptibility artefacts. Here we demonstrated that high quality MRI and fMRI images of the spinal cord could be obtained at 16.4T during SCS with recently developed MB-SWIFT. This is the first study that attempts spinal cord fMRI during SCS in rats.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.