Meeting Banner
Abstract #0705

Hypercapnia-induced vasodilatation increases brain stiffness

Stefan Hetzer1,2, Karl Bormann1, Florian Dittmann3, Philipp Sonnenschein1,2, Sebastian Hirsch1,2, Jürgen Braun4, and Ingolf Sack3

1Berlin Center for Advanced Neuroimaging, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Bernstein Center for Computational Neuroscience, Berlin, Germany, 3Institute of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 4Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany

Cerebral MR elastography paired with arterial spin labelling was applied to a group of healthy male subjects during a hypercapnia challenge to analyze the interrelation between cerebral blood flow and mechanical properties of brain tissue in vivo. Hypercapnia-induced vasodilation and the associated increase in blood perfusion was accompanied by a highly significant increase in global cerebral stiffness by 3% (p<0.0001).

This abstract and the presentation materials are available to members only; a login is required.

Join Here