Pericardial late gadolinium enhancement was correlated with pathologic specimens in 52 patients who had pericardiectomy performed for constrictive or chronic pericarditis. Pericardial LGE is an indicator of pericardial inflammation; however, it does not reliably distinguish inflammation from fibrosis: LGE was seen in 9/10 patients with pericardial fibrosis and minimal or no pericardial inflammation. Pericardial edema or early pericardial enhancement may be more useful biomarkers for pericardial inflammation.
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