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Abstract #0764

Quantitative myocardial perfusion using multi-echo Dixon for respiratory motion correction and arterial input function estimation

Markus Henningsson1, Alexandre Farias1,2,3, Adriana Dolores Maria Villa1, Cian Scannell1, Torben Schneider4, and Amedeo Chiribiri1

1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Federal University of Minas Gerais, Belo Horizonte, Brazil, 3Federal Center for Technological Education of Minas Gerais, Belo Horizonte, Brazil, 4Philips Healt Systems, London, United Kingdom

A quantitative myocardial first-pass perfusion approach is proposed using multi-echo Dixon acquisition. The fat images (unaffected by contrast bolus) are used to estimate respiratory motion and the transformations are applied to the corresponding diagnostic water images. The three echo images are also used to perform T2* correction of the arterial input function. Evaluation was performed in 8 patients during free-breathing rest perfusion. Motion correction reduced quantiation variability, while T2* correction of the arterial input function reduced the myocardial blood flow by 0.7ml/g/min across all patients.

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