Abstract #0769

Prediction for development of cerebral hyperperfusion after carotid endarterectomy using cerebral oxygen extraction fraction map based on quantitative susceptibility mapping at 7T

Jun-ichi Nomura¹, Ikuko Uwano², Makoto Sasaki², Kohsuke Kudo³, Fumio Yamashita², Kenji Ito², Shunrou Fujiwara¹, Yoshiyasu Matsumoto¹, Kohki Oikawa¹, Kohei Chida¹, Kazunori Terasaki⁴, Masakazu Kobayashi¹, Kenji Yoshida¹, and Kuniaki Ogasawara¹

¹Neurosurgery, Iwate Medical university, Morioka, Japan, ²Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical university, Yahaba, Japan, ³Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, ⁴Cyclotron Reserch Center, Iwate Medical university, Takizawa, Japan

The aim of this study was to validate whether preoperative QSM-based OEF (OEF_QSM) map at 7T could predict the development of postoperative hyperperfusion (HP) after carotid endarterectomy (CEA) in patients with internal carotid artery stenosis. In quantitative assessment, OEF_QSMwas significantly higher in the presence group than that in the absence group of HP. Receiver operating characteristic analysis showed the OEF_QSM was a good indicator for predicting the development of HP after CEA when the suitable cut-off value. Finally, the present study demonstrated that preoperative OEF_QSMmap at 7T can identify patients at risk for HP after CEA.

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