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Abstract #0769

Prediction for development of cerebral hyperperfusion after carotid endarterectomy using cerebral oxygen extraction fraction map based on quantitative susceptibility mapping at 7T

Jun-ichi Nomura1, Ikuko Uwano2, Makoto Sasaki2, Kohsuke Kudo3, Fumio Yamashita2, Kenji Ito2, Shunrou Fujiwara1, Yoshiyasu Matsumoto1, Kohki Oikawa1, Kohei Chida1, Kazunori Terasaki4, Masakazu Kobayashi1, Kenji Yoshida1, and Kuniaki Ogasawara1

1Neurosurgery, Iwate Medical university, Morioka, Japan, 2Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical university, Yahaba, Japan, 3Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, 4Cyclotron Reserch Center, Iwate Medical university, Takizawa, Japan

The aim of this study was to validate whether preoperative QSM-based OEF (OEFQSM) map at 7T could predict the development of postoperative hyperperfusion (HP) after carotid endarterectomy (CEA) in patients with internal carotid artery stenosis. In quantitative assessment, OEFQSM was significantly higher in the presence group than that in the absence group of HP. Receiver operating characteristic analysis showed the OEFQSM was a good indicator for predicting the development of HP after CEA when the suitable cut-off value. Finally, the present study demonstrated that preoperative OEFQSM map at 7T can identify patients at risk for HP after CEA.

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