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Abstract #0770

Investigating the use of non-contrast enhanced Magnetic Resonance Multi-Sequence Thrombus Imaging (MSTI) to direct therapy in patients with acute iliofemoral Deep Vein Thrombosis

Justinas Silickas1, Prakash Saha1, Alberto Smith1, Stephen Black2, Adam Gwozdz1, Marcelo Andia Kohnenkampf3, Ashish Patel1, Bijan Modarai1, Rene Botnar4, and Alkystis Phinikaridou4

1Academic Department of Vascular Surgery, King's College London, London, United Kingdom, 2Vascular Surgery Department, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom, 3School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile, 4School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Deep vein thrombosis (DVT) affects 1 in 1000 people and when the ilio-femoral segment is involved, over half will develop post-thrombotic syndrome (PTS). PTS can be debilitating for the patients and carries a huge health cost burden. Thrombolysis reduces the incidence of PTS, but is only successful in 60% of patients. There is no reliable method of identifying thrombi susceptible to lysis. We have developed a non-contrast-enhanced magnetic resonance multi-sequence thrombus imaging (MSTI) protocol that provides information on the structural composition of the thrombus and may be a reliable method of predicting thrombus lysability.

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