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Abstract #0813

Elastography, T2-mapping, and Dixon MRI of the gluteus maximus muscle in spinal cord injured and able-bodied subjects

Jules Laurent Nelissen1,2,3, Dorien Verschuren1, Maurits Sloots4, Larry de Graaf1, Jitsha Monte3, Sandra van den Berg3, Kevin Moerman5, Klaas Nicolay1, Mario Maas3, Sicco Bus6, Ralph Sinkus7, Jurgen Runge3,7, Christof Smit4, Thomas Janssen4,8, Cees Oomens1, Gustav Strijkers2, and Aart Nederveen3

1Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, 2Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, Netherlands, 3Radiology and Nuclear Medicine, Academic Medical Center, Amsterdam, Netherlands, 4Reade, Centre for Rehabilitation and Rheumatology, Amsterdam, Netherlands, 5Center for Extreme Bionics, Media lab, MIT, Cambridge, MA, United States, 6Department of Rehabilitation, Academic Medical Center, Amsterdam Movement Sciences, Amsterdam, Netherlands, 7Image Sciences & Biomedical Engineering, King’s College London, London, United Kingdom, 8Human Movement Sciences, VU University, Amsterdam, Netherlands

Gluteus maximus biomechanical properties and composition are altered in spinal cord injured (SCI) subjects and increase the risk of deep tissue injury type of pressure ulcers. For this purpose, a multi-parametric MRI study of the gluteus maximus of SCI and able-bodied subjects was performed. The protocol consisted of MRE, T2-mapping, and Dixon. The gluteus maximus of SCI subjects had a lower stiffness, which was accompanied by a higher fat fraction, as compared to the able-bodied subjects. The proposed protocol has great potential in providing personalized information on deep tissue injury risk.

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