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Abstract #0819

Quantitative T2 mapping of the thigh muscles and its correlation with the ADC: a feasibility study in assessing inflammatory myopathy

Fengdan Wang1, Qian Wang2, Haiping Zhang1, Dong Liu1, Tobias Kober3, Tom Hilbert3, Yi Sun4, Yan Zhang1, and Zhengyu Jin1

1Radiology, Peking Union Medical College Hospital, Beijing, China, 2Rheumatology, Peking Union Medical College Hospital, Beijing, China, 3Advanced Clinical Imaging Technology, Siemens Healthcare, AG, Switzerland, 4MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China

We investigated the use of the T2 mapping technique to quantitatively evaluate the thigh muscles of 18 dermatomyositis (DM)/polymyositis (PM) patients and 10 healthy control subjects. Moreover, the correlation of T2 values with apparent diffusion coefficient (ADC) values was also studied. The results showed significantly elevated T2 values with edematous muscles and increased T2 values with unaffected muscles (normal appearing in conventional MRI) in DM/PM patients, compared to the control group. The T2 values of the edematous muscles were found to be closely correlated with the ADC. This study demonstrated that T2 mapping may be successfully used in the quantitative evaluation of inflammatory myopathy.

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