Purpose: To analyze the fiber bundle architecture via white matter connectomes of extremely preterm (EP) born adolescents generated by Synthetic-MRI based white matter fibrography, and to study associations with summary measures of intelligence quotient (IQ) and executive function (EF). Methods: Eleven EP adolescents were scanned the tri-turbo spin echo pulse sequence, which is the concatenation of dual-echo TSE and single-echo TSE pulse sequences, both acquired with same geometry and scanner settings. Results: Connectome were successfully created for all subjects. Conclusion: White matter fibrography is a direct and reliable method for generating whole-brain white matter connectomes in adolescents born EP, and appears to have clinical relevance.
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