Perinatal hypoxic ischemic brain injury remains a significant cause of neonatal morbidity and mortality. Accurate prediction of neurodevelopmental outcome following HIE is important for parental counselling and directing care towards optimised treatments. Proton MRS derived thalamic Lactate/N-acetylaspartate (Lac/NAA) peak area ratio at 1.5T was a robust MR outcome biomarker in the pre-cooling era; a cut off Lac/NAA of 0.29 accurately predicted outcome. The aim of this work is to identify the cut off threshold of thalamic Lac/NAA at 3T in the cooling era for outcome prediction.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords