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Abstract #0861

High-Resolution, Non-contrast Pseudo-Continuous Arterial Spin-Labeling (PCASL) MR-Angiography compared to standard clinical MRI in the detection of intracranial vessel pathologies with emphasis on intracranial arteriovenous shunts.

Tilman Schubert1, oliver Wieben2, Patrick Turski2, Huimin Wu3, and Kevin Johnson2

1Radiology, Basel University Hospital, Basel, Switzerland, 2University of Wisconsin Madison, Madison, WI, United States, 3William Beaumont Hospital, Royal Oak, MI, United States

The detection of intracranial AV-shunts may be difficult with non-invasive imaging. Due to the nature of spin-labeled protons, ASL-based MRA is likely to be highly specific for AV-shunting. We sought to determine the sensitivity and specificity of ASL-based MRA in a group of 32 patients, among those 14 with AV-shunts. Furthermore, the diagnostic performance for vascular pathology not associated with AV-shunting was assessed. We found ASL-based MRA to be more specific with an equivalent sensitivity compared to a clinical MRA-exam for intracranial AV-shunts. All vascular pathology not associated with AV-shunting were detected with ASL-based and clinical MRA.

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