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Abstract #0862

Characteristics of Plaques and Lenticulostriate Arteries in Stroke Patients by Whole-Brain Vessel Wall Magnetic Resonance Imaging

Fang Wu1, Zhaoyang Fan2, Tianyi Qian3, Qi Yang1, and Debiao Li2

1Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China, 2Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States, 3MR Collaboration NEA, Siemens Healthcare, Beijing, China

The aim of our study was to investigate the plaque characteristics and the lenticulostriate artery (LSA) status in artery-to-artery (A-to-A) embolism and branch atheromatous disease (BAD) using whole-brain high-resolution MRI. The results showed that patients with A-to-A embolism presented more frequently hyperintense plaques (HIP), plaque surface irregularity, and severe stenosis than patients with BAD. A signi´Čücant reduction in the number and lengths of LSA branches in patients with BAD compared to A-to-A embolism was also found. Multivariate analysis further demonstrated that HIP was independently associated with A-to-A embolism, whereas the reduction in LSA branches was independently associated with BAD.

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