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Abstract #0864

Intravoxel Incoherent Motion (IVIM) Perfusion Imaging in Hyperacute Stroke: Initial Results

Christian Federau1, Max Wintermark2, Soren Christensen3, David Marcellus2, Guangming Zhu2, Maarten Lansberg3, Gregory Albers3, and Jeremy Heit2

1University Hospital Basel, Basel, Switzerland, 2Neuroradiology, Stanford University, Stanford, CA, United States, 3Neurology, Stanford University, Stanford, CA, United States

Intravoxel Incoherent Motion (IVIM) MR perfusion is of particular interest in stroke because it derives intrinsic microvascular perfusion information, and might therefore include information regarding collateral blood flow without being influenced by time delay in blood arrival, which is a limitation of other perfusion techniques. In this preliminary work in 23 patients with hyperacute stroke, we found the IVIM microvascular perfusion paramteters were significantly reduced in the infarct core but not in the penumbra, compared to the contralateral side, suggesting that at time of imaging, microvascular perfusion is maintained through collateral blood flow in the penumbra.

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