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Abstract #0865

Superselective 4D MR Angiography with Pseudo-Continuous Arterial Spin Labelling Combined with CENTRA-Keyhole (SS-4D-PACK) Used to Visualize Brain Arteriovenous Malformations

Osamu Togao1, Akio Hiwatashi1, Makoto Obara2, Michael Helle3, Koji Yamashita1, Daichi Momosaka1, Tatsuhiro Wada4, Hiroo Murazaki4, Marc Van Cauteren2, and Hiroshi Honda1

1Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 2Philips Japan, Tokyo, Japan, 3Philips Research, Hamburg, Germany, 4Division of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan

In the present study, we demonstrated the utility of superselective 4D-MR angiography with pCASL combined with CENTRA-keyhole (SS-4D-PACK) for the visualization of brain AVMs. This method enables a time-resolved and vessel-selective angiography within 5 minutes without a use of contrast agents. It was showed that almost perfect vessel selectivity was achieved with SS-4D-PACK. Although CNRs were slightly reduced in SS-4D-PACK due to a labeling loss during superselective label focusing, this was acceptable since visualization was well preserved. SS-4D-PACK can be a non-invasive clinical tool for assessing brain AVMs.

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