Abstract #0865

Superselective 4D MR Angiography with Pseudo-Continuous Arterial Spin Labelling Combined with CENTRA-Keyhole (SS-4D-PACK) Used to Visualize Brain Arteriovenous Malformations

Osamu Togao¹, Akio Hiwatashi¹, Makoto Obara², Michael Helle³, Koji Yamashita¹, Daichi Momosaka¹, Tatsuhiro Wada⁴, Hiroo Murazaki⁴, Marc Van Cauteren², and Hiroshi Honda¹

¹Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, ²Philips Japan, Tokyo, Japan, ³Philips Research, Hamburg, Germany, ⁴Division of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan

In the present study, we demonstrated the utility of superselective 4D-MR angiography with pCASL combined with CENTRA-keyhole (SS-4D-PACK) for the visualization of brain AVMs. This method enables a time-resolved and vessel-selective angiography within 5 minutes without a use of contrast agents. It was showed that almost perfect vessel selectivity was achieved with SS-4D-PACK. Although CNRs were slightly reduced in SS-4D-PACK due to a labeling loss during superselective label focusing, this was acceptable since visualization was well preserved. SS-4D-PACK can be a non-invasive clinical tool for assessing brain AVMs.

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