An optimised subtraction approach is developed to improve the background signal suppression in subtractive Non-Contrast-Enhanced MR Angiography (NCE-MRA) and Venography (NCE-MRV) techniques. Principal component analysis (PCA) is used to correct the intensity difference of background tissue in dark-blood images (DBIs) and bright-blood images (BBIs). Compared with the direct subtraction operation, the proposed approach significantly improved the background signal suppression in all the evaluated cases including femoral Fresh Blood Imaging (FBI)-MRA, iliac Flow-Sensitive Dephasing (FSD)-MRV and FSD-MRA for the thoracic central veins.
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