Abstract #0997

MRI Cine-Tagging of Cardiac-Induced Motion: Diagnostic Performance for Noninvasive Staging of Liver Fibrosis

Thierry Lefebvre¹, Léonie Petitclerc^1,2,3, Laurent Bilodeau^1,3, Giada Sebastiani⁴, Hélène Castel⁵, Claire Wartelle-Bladou⁵, Bich Ngoc Nguyen^6,7, Guillaume Gilbert^3,8, and An Tang^1,3

¹Centre de recherche du centre hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada, ²Leiden University Medical Centre (LUMC), Leiden, Netherlands, ³Department of Radiology, Radio-Oncology and Nuclear Medicine, Université de Montréal, Montreal, QC, Canada, ⁴Department of Medicine, Division of Gastroenterology, McGill University Health Centre (MUHC), Montreal, QC, Canada, ⁵Department of Gastroentology and Hepatology, Université de Montréal, Montreal, QC, Canada, ⁶Department of Pathology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, QC, Canada, ⁷Department of Pathology and Cellular Biology, Université de Montréal, Montreal, QC, Canada, ⁸MR Clinical Science, Philips Healthcare Canada, Markham, ON, Canada

Elastography techniques for staging liver fibrosis assess the right liver and require additional hardware. MRI cine-tagging evaluates the strain of liver tissue and shows promise for staging liver fibrosis without additional hardware. It can be performed routinely during MRI examinations. Strain showed high correlation with fibrosis stages (ρ = -0.60, P < 0.001). AUC was 0.78 to distinguish fibrosis stages F0 vs. ≥ F1, 0.78 for ≤ F1 vs. ≥ F2, 0.87 for ≤ F2 vs. ≥ F3, and 0.87 for ≤ F3 vs. F4. Larger studies in cohorts with specific liver disease are required to validate this technique.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.