Abstract #1020

Optimized 3D Stack-of-Spirals MR Fingerprinting with Hybrid Sliding-Window and GRAPPA Reconstruction

Congyu Liao^1,2, Berkin Bilgic², Mary Kate Manhard², Xiaozhi Cao¹, Jianhui Zhong¹, Lawrence L Wald², and Kawin Setsompop²

¹Department of Biomedical Engineering, Zhejiang University, Hangzhou, China, ²Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States

We demonstrate 3D stack-of-spiral MRF acquisition with hybrid sliding-window and GRAPPA (SW+GRAPPA) reconstruction using a constant density spiral (CDS) rather than standard variable density spiral (VDS). The CDS was found to mitigates high-frequency artifacts after in-plane sliding-window (SW) combination and improve the subsequent GRAPPA and dictionary matching reconstruction. The proposed 3D constant density stack-of-spiral MRF allows whole-brain (240×240×192 mm³) parametric mapping at 1 mm isotropic resolution with high quality in 8 minutes.

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