Abstract #1026

Quantitative Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of Knee Osteoarthritis (OA)

Yajun Ma¹, Lidi Wan¹, Xin Cheng¹, Yinghua Zhao¹, Eric Y Chang^1,2, and Jiang Du¹

¹University of California, San Diego, San Diego, CA, United States, ²VA San Diego Healthcare System, San Diego, CA, United States

In this study we aimed to develop a comprehensive quantitative UTE imaging package including UTE-Cones actual flip angle imaging (UTE-Cones-AFI) for accurate B1 mapping, UTE-Cones variable flip angle (UTE-Cones-VFA) for T₁ mapping, 3D UTE-Cones-MT for MT modeling, UTE-Cones-AdiabT1rho for T1r mapping, and multi-echo UTE-Cones for T2* mapping. The techniques were evaluated on cadaveric human knee joints.

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