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Abstract #1045

Isotropic resolution DTI of lower back nerves using a phase-corrected diffusion-prepared 3D TSE

Barbara Cervantes1, Anh Van2, Dominik Weidlich1, Hendrik Kooijman3, Andreas Hock3, Ernst Rummeny1, Alexandra Gersing1, Jan Kirschke4, and Dimitrios Karampinos1

1Interventional and Diagnostic Radiology, Technical University of Munich, Munich, Germany, 2Institute of Medical Engineering, Technical University of Munich, Garching, Germany, 3Philips Healthcare, Hamburg, Germany, 4Interventional and Diagnostic Neuroradiology, Technical University of Munich, Munich, Germany

Diffusion-prepared 3D TSE (dprep-3D TSE) has been applied for isotropic-resolution distortion-free proximal- and peripheral-nerve DWI. Dprep-3D TSE has been combined with magnitude stabilizers to reduce magnitude modulation induced by motion and eddy currents and has used velocity compensation to reduce motion-induced phase modulation in diffusion-weighted signals. However, due to the multi-shot nature of dprep-3D TSE, remaining motion-induced phase leads to image and DTI-parameter artifacts and requires phase navigation. The purpose of this work is to develop a phase-navigation and phase-correction scheme for dprep-3D TSE and to apply the developed method in vivo for isotropic-resolution DTI of lumbosacral and sciatic nerves.

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