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Abstract #1046

Simultaneous Multislice Accelerated Diffusion-Tensor Imaging of Thigh Muscles in Myositis

Fengdan Wang1, Chanyuan Wu2, Caiyuan Sun1,3, Dong Liu1, Yi Sun4, Qian Wang2, and Zhengyu Jin1

1Radiology, Peking Union Medical College Hospital, Beijing, China, 2Rheumatology, Peking Union Medical College Hospital, Beijing, China, 3Radiology, Shenzhen Sun Yat-Sen Cardiovascular Hospital, Shenzhen, China, 4MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China

We investigated the clinical feasibility of using simultaneous multislice accelerated echo planar imaging diffusion-tensor imaging (SMS-EPI-DTI) to image thigh muscles of both 10 healthy control subjects and 20 dermatomyositis (DM)/ polymyositis (PM) patients. This technique yielded a reduced scan time to only about five minutes. The results showed that the tractographic imaging and DTI-derived parameters of edematous muscles differed among affected and unaffected muscles of the DM/PM patients and normal muscles of the control subjects. In conclusion, SMS-EPI-DTI is clinically feasible for imaging thigh muscles and quantitatively evaluating edematous muscles of DM and PM patients.

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