Abstract #1046

Simultaneous Multislice Accelerated Diffusion-Tensor Imaging of Thigh Muscles in Myositis

Fengdan Wang¹, Chanyuan Wu², Caiyuan Sun^1,3, Dong Liu¹, Yi Sun⁴, Qian Wang², and Zhengyu Jin¹

¹Radiology, Peking Union Medical College Hospital, Beijing, China, ²Rheumatology, Peking Union Medical College Hospital, Beijing, China, ³Radiology, Shenzhen Sun Yat-Sen Cardiovascular Hospital, Shenzhen, China, ⁴MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China

We investigated the clinical feasibility of using simultaneous multislice accelerated echo planar imaging diffusion-tensor imaging (SMS-EPI-DTI) to image thigh muscles of both 10 healthy control subjects and 20 dermatomyositis (DM)/ polymyositis (PM) patients. This technique yielded a reduced scan time to only about five minutes. The results showed that the tractographic imaging and DTI-derived parameters of edematous muscles differed among affected and unaffected muscles of the DM/PM patients and normal muscles of the control subjects. In conclusion, SMS-EPI-DTI is clinically feasible for imaging thigh muscles and quantitatively evaluating edematous muscles of DM and PM patients.

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