Combining multi-band slice selection with COKE (COherent K-t-space EPSI) for accelerated spectral imaging

One of the powerful techniques for faster spectroscopic imaging acquisition is so called proton echo planar spectroscopic imaging (EPSI). An alternative method, which we here term COKE (COherent K-t space EPSI), relies on interleaving “blipped” PE gradients in between readouts to produce coherent phase between the k-t space lines. COKE enables to double the SW in comparison to EPSI or to halve the acquisition duration. We designed a sequence that integrates a multi-band CAIPIRINHA with COKE acquisition for faster spectroscopic imaging. This was demonstrated in both phantoms and in-vivo.