Abstract #1062

Dynamically Switched B0 Field Control for Separate Optimization of Tailored Volume Lipid Suppression and B0 Homogeneity for Brain Chemical Shift Imaging at 3T using Multi-Coil Shim Array

Nicolas Arango¹, Jason P. Stockman^2,3, Bernhard Strasser², Borjan Gagoski^3,4, Ovidiu Andronesi², Lawrence L. Wald^2,3, Jacob White¹, and Elfar Adalsteinsson^1,5

¹Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ²A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospita, Charlestown, MA, United States, ³Department of Radiology, Harvard Medical School, Boston, MA, United States, ⁴Fetal Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA, United States, ⁵Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States

A rapidly reconfigurable 32-channel local-multi-coil-shim-array is used to both enhance lipid suppression and narrow metabolite linewidth in chemical-shift imaging of the brain. Using in-situ optimization, the array is first configured to widen the spectral gap between spatially separate lipid and metabolite regions, to improve lipid-surpressing inversion, and then reconfigured for field homogeneity, to narrow metabolite linewidth during readout. For 2cm thick brain slab, using the dynamically-reconfigured array reduced lipid contamination by 24.5%, reduced linewidth by 34%, and increased well-imaged brain area by 38% over static 2^ndorder shimming

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