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Abstract #1062

Dynamically Switched B0 Field Control for Separate Optimization of Tailored Volume Lipid Suppression and B0 Homogeneity for Brain Chemical Shift Imaging at 3T using Multi-Coil Shim Array

Nicolas Arango1, Jason P. Stockman2,3, Bernhard Strasser2, Borjan Gagoski3,4, Ovidiu Andronesi2, Lawrence L. Wald2,3, Jacob White1, and Elfar Adalsteinsson1,5

1Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 2A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospita, Charlestown, MA, United States, 3Department of Radiology, Harvard Medical School, Boston, MA, United States, 4Fetal Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA, United States, 5Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States

A rapidly reconfigurable 32-channel local-multi-coil-shim-array is used to both enhance lipid suppression and narrow metabolite linewidth in chemical-shift imaging of the brain. Using in-situ optimization, the array is first configured to widen the spectral gap between spatially separate lipid and metabolite regions, to improve lipid-surpressing inversion, and then reconfigured for field homogeneity, to narrow metabolite linewidth during readout. For 2cm thick brain slab, using the dynamically-reconfigured array reduced lipid contamination by 24.5%, reduced linewidth by 34%, and increased well-imaged brain area by 38% over static 2nd order shimming

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